Aripiprazole is an organic compound

2024-01-16


Aripiprazole, an organic compound with the chemical formula C23H27Cl2N3O2, is mainly used as an antipsychotic drug for the treatment of various types of schizophrenia. Foreign clinical trials have shown that aripiprazole has a significant effect on both positive and negative symptoms of schizophrenia, and can also improve the accompanying emotional symptoms and reduce the recurrence rate of schizophrenia.
This product is a new type of atypical anti-schizophrenia drug, which has a two-way regulatory effect on the DA nervous system and is a stabilizer of DA transmitters. It has high affinity for D2, D3, 5-HT1A, and 5-HT2A receptors. The antischizophrenic effects are produced by partial agonism of D2 and 5-HT1A receptors and antagonism of 5-HT2A receptors. After oral administration, the peak time of blood concentration is 3~5 hours, and the half-life is 48~68 hours. The dehydroaripiprazole was the main active metabolite.
For the treatment of various types of schizophrenia. Foreign clinical trials have shown that this product has a significant effect on the positive and negative symptoms of schizophrenia, and can also improve the accompanying emotional symptoms and reduce the recurrence rate of schizophrenia.